Study of Mg-Hydroxyapatite Composite with various composition of Hydroxyapatite which obtained From Cow Bones in Simulation Body Fluid (SBF)
Keywords:
Keywords— Magnesium, hydroxyapatite from cow bone, compositesAbstract
The objective of the present study was to synthesize biodegradable Mg-hydroxyapatite (Mg-HAp) composites for bone replacement. Hydroxyapatite (HAp) powders were synthesized from bioresources cow bone in a cost effective and ecofriendly way. Cow bone was converted to hydroxyapatite by a heat treatment method at different temperatures. Hydroxyapatite was characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM), Energy Dispersive X-Ray spectroscopy (EDX) and FT-IR. The results show a uniform distribution of HAp with a crystal size range of 400-800 nm. The Mg–HAp composites were prepared by mixing different amounts of HAp powders to Mg powder and finally the powder was pressed to make samples. The microstructure of Mg–HAp composite was examined by optical microscope (OM).The results show a uniform distribution of HAp particles along the boundary between matrix particles.. The relative densities of the composites initially increased with increase the amount of HA addition. The theoretical and experimental hardness of the composites are compared with the addition of 3 to 9 wt% HAp. Addition of HAp decreases the crystal size of the nanocomposites. The mechanical properties, i.e. hardness is evidently increased with increasing HAp content up to 5 wt%.
Â
References
Kannan B.M, Raman S.R.K. In vitro degradation and mechanical integrity of calcium containing magnesium alloys I modified Simulated Body Fluid: Biomaterials , 29, 14,2003
Staiger M P, Pietak A M, Huadmai J and Dias G . Magnesium and its alloys as orthopedic biomaterials: a review . Biomater : 27, 1728,2006
Witte F., Kaese V., H. HaferkamP, E. Switzer, A. Meyer-Lidenberg, C.J. Wirth, H. Windhagen. In Vivo Corrosion of Four Magnesium Alloys and The Associated Bone Response" : Biomaterials, 26,3557 , 2005
Witte F., Reinfenrath J., Muller P'P.,Crosstack H-A., Nellesen J., Bach F.W., Bormann D, Rudert M. ,,Cartilage Repair on Magnesium Scaffolds Used as a Subchondral Bone : Replacement". Mateialwissenschaft und Weksrffiechnik : 37 (6), 504-508', 2006
Yu G, Zhang E, Pan F, Yang K, : In vivo corrosion behavior of Mg-Mn-Zn alloy for bone implant application J. Biomed. Mater. Res. 83, 703, 2007
Song G, Corros. Sci., Recent progress in corrosion and protection of magnesium alloys, 49, 1696.2007
Jarcho M, Bolen C.H, Thomas M.B, Bobick J, Kay J F, Doremus R H., J. Mater. : Hydroxylapatite synthesis and characterization in dense polycrystalline form.Sci., 11, 2027. 1976
Khalil K. A, Kim S W, Dharmaraj N, Kim H Y., : Corrosion Passivation in Simulated Body Fluid of Magnesium/ Hydroxyapatite Nanocomposites Sintered by High Frequency Induction Heating Int. J. Appl. Ceram. Techol., 8, 523, 2011
Kim S W, Cockcroft S.L, Khalil K. A, Ogi K, A-structural Materials Properties microstructure and Processing Mater. Sci. Eng. A, 527, 4926, 2010
Khalil K. A, Kim S W, Kim H Y, Novel mechanism to improve toughness of the hydroxyapatite bioceramics using high-frequency induction heat sintering, Mater. Sci. Eng. A, 456, 368. 2007
X. Gu, W. Zhou, Y. Zheng, L. Dong, Y. Xi, D. Chai, A study on alkaline heat treated Mg–Ca alloy for the control of the biocorrosion rate. Mater. Sci..Eng. C 30, 827,832, 2010
Ooi, C. Y.; Hamdi, M.; Ramesh, S. Properties of hydroxyapatite produced by annealing of bovine bone. Ceram. Int. : 33, 1171-1177, 2007
Dachun, L.; Wei, C. Preparation and characterization of natural hydroxyapatite from animal hard tissues. Key Eng. Mat.: 342, 343, 2007
Ivankovic, H.; Gallego Ferrer, G.; Tkalcec, E.; Orlic, S.; Ivankovic, M. Preparation of highly porous hydroxyapatite from cuttlefish bone. J. Mater. Sci.-Mater. Med: 20, 1039-1046, 2009
Kim, S.; Park, P.; Kim, Y. Study on acute subcutaneous toxicity of hydroxyapatite sinter produced from tuna bone in Sprague—Dawly rats. Korean J. Life Sci.: 11, 97–10, 2001
Manalu J L, Soegijono B, Indrani D J, Characterization of Hydroxyapatite Derived from Bovine Bone Asian Journal of Applied Sciences : 3(4), 758-765, 2015
Downloads
Published
How to Cite
Issue
Section
License
- Papers must be submitted on the understanding that they have not been published elsewhere (except in the form of an abstract or as part of a published lecture, review, or thesis) and are not currently under consideration by another journal published by any other publisher.
- It is also the authors responsibility to ensure that the articles emanating from a particular source are submitted with the necessary approval.
- The authors warrant that the paper is original and that he/she is the author of the paper, except for material that is clearly identified as to its original source, with permission notices from the copyright owners where required.
- The authors ensure that all the references carefully and they are accurate in the text as well as in the list of references (and vice versa).
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Attribution-NonCommercial 4.0 International that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- The journal/publisher is not responsible for subsequent uses of the work. It is the author's responsibility to bring an infringement action if so desired by the author.