Anthelmintic Activities of Spondias mombin Leaves and Fruits Extracts against Trichostrongylid Nematodes in Goats
Keywords:
anthelmintic activity, Spondias mombin, trichostrongylid nematodes, sheep, goats, LC50Abstract
This research was carried out to determine the anthelmintic activity of Spondias mombin against trichostrongylid nematodes from goats and sheep. To achieve the purpose, Spondias fruits and leaves were used and their effect on mortality rates of trychostrongylid L3 larvae were observed. Two different extract methods, the chloroform and 80% methanol extractions were used to extract the fruits and leaves. Results showed that the LC50 of S. mombin leaves extracts were lower for both chloroform and 80% methanol extractions than its fruits. The LC50 values for the leaves extract were 0.158mg/ml and 1.279mg/ml respectively for both methods. Whereas the LC50 of the S. mombin fruits extracts were 0.416mg/ml and 2.200mg/ml for chloroform and 80% methanol extracts respectively. This indicated that S. mombin leaf was more toxic compared to its fruits extract. The differences between concentrations were statistically significant (p<0.05). Anthelmintic activities of S. mombin increased with concentration.
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