An Innovative Method for the Extraction of Phenolic Compounds from <i>Polygonum Cuspidatum</i>
Keywords:extraction, SCCO2, co-solvent, polygonum cuspidatum
AbstractSupercritical CO2 extraction of resveratrol, rutin, and quercetin from Polygonum cuspidatum was performed in laboratory scale extraction system with ethanol or water as co-solvent. In this work, the effect of operating parameters such asÂ co-solvent concentration, pressure and temperature onÂ extraction yield were investigated. Extraction were carried out at temperatures of 40-80oC, pressures of 10-40 MPa with a fixed CO2 flow rate (3 mL/min) and extraction time (3 h). The results showed that the presence of ethanol and water as co-solvent could enhance the solvent power or the selectivity of SCCO2 to extract resveratrol, rutin, and quercetin. The increasing concentration of ethanol and water affected the extraction yield of them. By changing the temperature and pressure, the vapor pressure enhancement of extractable compounds increase analyte solubility. This result revealed that SCCO2 extraction with co-solvent is applicable method for extraction of bioactive compounds of plant and may lead to an advanced plant biomass components extraction technology.
Shan, B., Cai, YZ., Brooks, JD., Corke, H., â€œAntibacterial properties of Polygonum cuspidatum roots and their major bioactive constituentsâ€, Food Chem., 109: pp.530â€“537, 2008.
Benova, B., Adam, M., Pavlikova, P., Fischer, J., â€œSupercritical fluid extraction of piceid, resveratrol and emodin from Japanese knotweedâ€, J. Supercrit. Fluids, 51: pp.325â€“330, 2010.
Du, FY., Xiao, XH., Li, GK., â€œApplication of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidatiâ€, J. Chromatogr. A, 1140: pp.56â€“62, 2007.
Zitka, O., Sochor, J., Rop, O., Skalickova, S., Sobrova, P., Zehnalek, J., Beklova, M., Krska, B., Adam, VV., Kizek, R., â€œComparison of Various Easy-to-Use Procedures for Extraction of Phenols from Apricot Fruitsâ€, Molecules, 16: pp.2914â€“2936, 2011.
Kaeberlein, M., â€œResveratrol and rapamycin: are they anti-aging drugs?â€, Bioessays, 32: pp.96â€“99, 2010.
Baumgertel, A., Grimm, R., Eisenbeiss, W., Kreis, W., â€œPurification and charakterization of flavonol 3-O-Î²-heterodisaccharidase from the dried herb of Fagopyrum esculentum Moenchâ€, Phytochem., 64: pp.411â€“418, 2003.
Yang, N., Ren, G., "Application of Near-Infrared Reflectance Spectroscopy to the Evaluation of Rutin and D-chiro-Inositol Contents in Tartary Buckwheat", J. Agric. Food. Chem., 56: pp.761â€“764, 2008.
de Boer, VCJ., Diha, AA., van der Woude, H., Arts, ICW., Wolffram, S., Alink, GM., Rietjens, I., Keijer, J., Hollman, PCH., "Tissue distribution of quercetin in rats and pigs", J. Nutr., 135: pp.1718â€“1725, 2005.
Careri, M., Corradini, C., Elviri, L., Nicoletti, I., Zagnoni, I., "Direct HPLC Analysis of quercetin end trans-resveratrol in red wine, grape and wine making by-products", J. Agric. Food. Chem., 51: pp.5226â€“5231, 2003.
Ignat, I., Volf, I., Popa, VI., "A critical review of methods for characterisation of polyphenolic compounds in fruits and vegetables", Food Chem., 126: pp.1821â€“1835, 2011.
Campomanes, AMF, Rostagno, MA., Meireles, MAA., "Production of polyphenol extracts from grape bagasse using supercritical fluids: Yield, extract composition and economic evaluation", J. Supercrit. Fluids, 77: pp.70â€“78, 2013.
Herrero, M., Cifuentes, A., Ibanez, E., "Sub- and supercritical fluid extraction of functional ingredients from different natural sources: plants, food-byproducts, algae and microalgae ? a review", Food Chem., 98: pp.136â€“148, 2006.
Rostagno, MA., Arrigo, MD., Martinez, JA., "Combinatory and hyphenated sample preparation for the determination of bioactive compounds in foods", Trends Anal. Chem., 29: pp.553â€“561, 2010.
Bleve, M., Ciurlia, L., Erroi, E., Lionetto, G., Longo, L., Rescio, L., Schettino, T., Vasapollo, G., "An innovative method for the purification of anthocyanins from grape skin extracts by using liquid and sub-critical carbon dioxide", Sep. Purif. Technol., 64: pp.192â€“197, 2008.
Casas, L., Mantell, C., Rodriguez, M., Martinez de la Ossa, EJ., Roldan, A., De Ory, I., Caro, I., Blandino, A., "Extraction of resveratrol from the pomace of Palomino fino grapes by supercritical carbon dioxide", J. Food Eng., 96: pp.304â€“308, 2010.
Serra, AT., Seabra, IJ., Braga, MEM., Bronze, MR., de Sousa, HC., Duarte, CMM., "Processing cherries (Prunus avium) using supercritical fluid technology. Part 1: Recovery of extract fractions rich in bioactive compounds", J. Supercrit. Fluids, 55: pp.184â€“191, 2010.
Serra, AT., Matias, AA., Almeida, APC., Bronze, MR., Alves, PM., de Sousa, HC., Duarte, CMM., "Processing cherries (Prunus avium) using supercritical fluid technology. Part 2. Evaluation of SCF extracts as promising natural chemotherapeutical agents", J. Supercrit. Fluids, 55: pp.1007â€“1013, 2011.
Formato, A., Gallo, M., Ianniello, D., Montesano, D., Naviglio, D., "Supercritical fluid extraction of Î±- and Î²-acids from hops compared to cyclically pressurized solid-liquid extraction", J. Supercrit. Fluids, 84: pp.113â€“120, 2013.
Chafer, A., Pascual-Marti, MC., Salvador, A., Berna, A., "Supercritical fluid extraction and HPLC determination of relevant polyphenolic compounds in grape skin", J. Sep. Sci., 28: pp.2050â€“2056, 2005.
Luque de Castro, MD., Garcia-Ayuso, LE., "Soxhlet extraction of solid materials: an outdated technique with a promising innovative future", Anal. Chim. Acta., 369: pp.1â€“10, 1998.
Hsu, CH., Chan, YP., "Antioxidant activity of extract from Polygonum cuspidatum", Biol. Res., 40: pp.13â€“21, 2007.
Benova, B., Adam, M., Onderkova, K., Krajicek, M., "Analysis of selected stilbenes in Polygonum cuspidatum by HPLC coupled with CoulArray detection", J. Sep. Sci., 31: pp.2404â€“2409, 2008.
Peng, W., Qin, R., Li, X., Zhou, H., "Botany, phytochemistry, pharmacology, and potential application of Polygonum cuspidatum Sieb.et Zucc.: A review", J. Ethnopharmacol., 148: pp.729â€“745, 2013.
de Campos Luanda, MAS., Fernanda, VL., Rozangela, CP., Sandra, RS., "Free radical scavenging of grape pomace extracts from Cabernet sauvingnon (Vitis vinifera)", Bioresour. Technol., 99: pp.8413â€“8420, 2008.
Yilmaz, EE., Ozvural, EB., Vural, H., "Extraction and identification of proanthocyanidins from grape seed (Vitis Vinifera) using supercritical carbon dioxide", J. Supercrit. Fluids, 55: pp.924â€“928, 2011.
Zarena, AS., Sachindra, NM., Sankar, KU., "Optimisation of ethanol modified supercritical carbon dioxide on the extract yield and antioxidant activity from Garcinia mangostana L.", Food Chem., 130: pp.203â€“208, 2012.
de Melo, MMR., Silvestre, AJD., Silva, CM., "Supercritical fluid extraction of vegetable matrices: Applications, trends and future perspectives of a convincing green technology", J. Supercrit. Fluids, 92: pp.115â€“176, 2014.
Reinoso, BD, Moure, A., Dominguez, H., Parajo, JC., "Supercritical CO2 Extraction and Purification of Compounds with Antioxidant Activity", J. Agric. Food. Chem., 54: pp.2441âˆ’2469, 2006.
Kim, WJ., Kim, JD., Kim, J., Oh, SG., Lee, YW., "Selective caffeine removal from green tea using supercritical carbon dioxide extraction", J. Food Eng., 89: pp.303â€“309, 2008.
Durante, M., Lenucci, MS., Mita, G., "Supercritical Carbon Dioxide Extraction of Carotenoids from Pumpkin (Cucurbita spp.): A Review", Int. J. Mol. Sci., 15: pp.6725â€“6740, 2014.
Mustafa, A., Turner, C., "Pressurized liquid extraction as a green approach in food and herbal plants extraction: A review", Anal. Chim. Acta., 703: pp.8â€“18, 2011.
Icen, H., Guru, M., "Effect of ethanol content on supercritical carbon dioxide extraction of caffeine from tea stalk and fiber wastes", J. Supercrit. Fluids, 55: pp.156â€“160, 2010.
Mezzomo, N., Mileo, BR., Friedrich, MT., Martinez, J., Ferreira, SRS., "Supercritical fluid extraction of peach (Prunus persica) almond oil: Process yield and extract composition", Bioresour. Technol., 101: pp.5622â€“5632, 2010.
Machmudah, S., Kitada, K., Sasaki, M., Goto, M., Munemasa, J., Yamagata, M., "Simultaneous Extraction and Separation Process for Coffee Beans with Supercritical CO2 and Water", Ind. Eng. Chem. Res., 50: pp.2227â€“2235, 2011.
Machmudah, S., Martin, A., Sasaki, M., Goto, M., "Mathematical modeling for simultaneous extraction and fractionation process of coffee beans with supercritical CO2 and water", J. Supercrit. Fluids, 66: pp.111â€“119, 2012
Porto, CD., Decorti, D., Natolino, A., "Water and ethanol as co-solvent in supercritical fluid extraction of proanthocyanidins from grape marc: A comparison and a proposal", J. Supercrit. Fluids, 87: pp.1â€“8, 2014.
How to Cite
- Papers must be submitted on the understanding that they have not been published elsewhere (except in the form of an abstract or as part of a published lecture, review, or thesis) and are not currently under consideration by another journal published by any other publisher.
- It is also the authors responsibility to ensure that the articles emanating from a particular source are submitted with the necessary approval.
- The authors warrant that the paper is original and that he/she is the author of the paper, except for material that is clearly identified as to its original source, with permission notices from the copyright owners where required.
- The authors ensure that all the references carefully and they are accurate in the text as well as in the list of references (and vice versa).
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Attribution-NonCommercial 4.0 International that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
- The journal/publisher is not responsible for subsequent uses of the work. It is the author's responsibility to bring an infringement action if so desired by the author.