Clitoromegaly with Associated Anomalies in the Female of a Fraternal Twin: A Case Report
Keywords:Ambiguous genitalia, clitoromegaly, female fraternal twin, karyotyping
We report this uncommon case of clitoromegaly with associated anomalies in a 2 months old female, the first of fraternal twins. The initial diagnosis of ambiguous genitalia on karyotyping was changed to clitoromegaly most probably due to congenital adrenal hyperplasia (CAH).
Karyotyping, biochemical analysis, ultrasonography, contrast studies and magnetic resonance imaging were done as the preoperative workup of this patient.
Clitoromegaly.2013. Retrieved from en.wikipedia.org/wiki/ Clitoromegaly
Dumont T, Black AY, Ahmet A, Fleming NA. Isolated transient neonatal clitoromegaly with hyperandrogenism of unknown aetiology. J Pediatr Adolesc Gynecol. 2009; 22(5): e 142-5(ISSN: 1873-4332).
Williams CE, Nakhal RS, Achermann JC, Creighton SM. Persistent unexplained congenital clitoromegaly in females born extremely premature. J Pediatr Urol. 2013; DOI 10.1016/j.jpurol.2013.03.001.
Geramizadeh B, Anbardar MH, Shakeri S. Clitoromegaly caused by cavernous haemangioma: A rare case report and review of literature. Urol Ann. 2012; 4:175-177.
Rink RC, Adams MC, Misseri R. A new classification for genital ambiguity and urogenital sinus anomalies.BJU International. 2005; 95(4)638-642:
Von Prader A. Der genitalbefund beim pseudohermaproditus feminus kongenitalen adrenogenitalen syndromes. Helv.Pediatr Acta 1954; 9:231-48
Gunther DF, Bukowski TP, Ritzen EM, Wedell A,Van Wyk JJ. Prophylactic adrenalectomy of a 3 year old girl with congenital adrenal hyperplasia: Pre-and post operatives studies. J Clin Endocrinol Metab. 1997 .82:3324-3327,.
Gleason PE. Urogenital Sinus and CloacalAnomalies. 2009. Retrieved from www.pediatricurologyinformation.com/uroGenital Sinus/topic.html.
Chowdhury LH, Saha N, Naq UK, Siddique FH, Khan NA. Congenital urogenital sinus anomaly without adrenal hyperplasia.Mymensingh Med J.2012; 21(4):752-724.
Elmore JM, Kirsch AJ, Snyder 111 HM. Congenital Urogynaecologic Anomalies. 2012. Retrieved from emedicine.medscape.com/article/1017296-overview#aw2aab6b3
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