Rosai-Dorfman's Disease Mimicking Nasopharyngeal Carcinoma: A Preliminary Case Report
Keywords:
Rosai-Dorfman, disease, nasopharyngeal, carcinomaAbstract
We report the case of a 28-year-old female Nigerian with Rosai-Dorfman disease mimicking Nasopharyngeal Carcinoma. Patient presented with bilateral cervical lymphadenopathy of 1 year duration, snoring of 3months duration and difficulty in breathing of 3days duration. Developed progressive worsening difficulty in breathing and restlessness. No history of weight loss, fever, or epistaxis. On physical examination, patient was in obvious respiratory distress, with signs of upper airway obstruction. Bilaterally enlarged lymph nodes at level 5 and non-tender. Throat examination showed an obvious postnasal mass on tongue depression with a metallic tongue deppressor.  Plain soft tissue neck radiograph revealed narrowed pharyngeal airway caused by a soft tissue mass. Patient was resuscitated and taken to the theatre for emergency tracheostomy, Examination Under Anaesthesia of the postnasal space showed a spherical firm mass which was biopsied. Histology report revealed the mass to be Rosai-Dorfman’s disease. Patient was commenced on low dose prednisolone and the mass is regressing.
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