A Proposed Algorithm for Determining the Suitable Number of Significant Digits of Force Transducer Calibration Constants
DOI:
https://doi.org/10.24203/ajas.v10i5.7072Keywords:
Significant digits, Force transducer, Rounding, uncertainty, calibration constantsAbstract
Precision measurement is one of the important goals of measurement and calibration. Positive measures are designed to provide researches with the highest accuracy and precision levels. In force measurements, force measuring instrument manufacturers are striving to achieve the best force measurement resolution to accompany the high level of calibration measurement capabilities achieved by the primary deadweight machines. In the calibration of the force transducers, polynomial equations which correlate, the applied load on the transducer and its corresponding output signal in mV/V are deduced. These equations contain numerical constants A, B and C. This paper introduces a mechanism to determine the suitable number of significant digits for these constants. Error analysis procedure for the calibration polynomial equation is proposed. This proposed algorithm safeguards the most accurate and realistic method for rounding the calibration constants
References
Rodr.guez LC et al. Estimation of performance characteristics of an analytical method
using the data set of the calibration experiment. Analytical Letters. 1993;26(6):16
DOI: 10.1080/00032719308019900
Gu H et al. Selecting the correct weighting factors for linear and quadratic calibration
curves with least-squares regression algorithm in bioanalytical LC-MS/MS assays and
impacts of using incorrect weighting factors on curve stability, data quality, and assay
performance. Analytical Chemistry. 2014;86(18):8959-8966'
DOI: 10.1021/ac5018265
Hayashi Y et al. Detection limit estimated from slope of calibration curve: An application
to competitive ELISA. Analytical Sciences. 2005;21(2):167-169
DOI: 10.5772/intechopen.72932
Zhao Y et al. Reasons for calibration standard curve slope variation in LC-MS assays and
how to address it. Bioanalysis. 2014;6(11):1439-1443
DOI:10.4155/bio.14.71
Oliveira EC. Internal standard versus external standard calibration: An uncertainty Case
study of a liquid chromatography analysis. Quimica Nova. 2010;33(4):19
DOI:10.1590/S0100-40422010000400041
Tan A, Awaiye K. Use of internal standards in LC-MS bioanalysis. In: Li W, Zhang J, Tse
FLS, editors. Handbook of LC-MS Bioanalysis: Best Practices, Experimental Protocols,
and Regulations. John Wiley & Sons Inc.; 2013. pp. 217-227
DOI:10.1002/9781118671276.CH17
Vicki Barwick Preparation of Calibration Curves A Guide to Best Practice " LGC/VAM/2003/032. Valid Analytical Measurement (VAM)
DOI: 10.13140/RG.2.2.36338.76488
Downloads
Published
Issue
Section
License
Copyright (c) 2022 Riham S. hegazy, Magdi Ibrahim, Gouda. M. Mahmoud
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright © The Author(s). This article is published under the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
