Study of Lipid Profile Parameter for Developing Hypertensive and Type 2 Diabetes Mellitus
Keywords:Hypertension, Cholesterol, Diabetes Mellitus, hyperlipoproteinaemia
This study was designed to find out the effect of non-hypertensive and hypertensive type 2 diabetes on lipid profile to determine whether these biochemical parameters were affected in individuals associated with these disease conditions. A total of one hundred and fifty one (151) individuals were subjected for the study. Of these thirty seven (37) were established hypertensive diabetics and thirty four (34) are established non-hypertensive diabetics. The established hypertensive non-diabetics were thirty eight (38) while forty two (42) were normal healthy individuals. The results showed that there was no significant differences (P>0.05) in the mean concentrations of cholesterol, triglycerides (TG), HDL-cholesterol, LDL-cholesterol and glucose between hypertensive diabetics and non-hypertensive diabetics studied. The study also demonstrated that, there were no significant differences (P>0.05) in the mean levels of all the parameters measured between hypertensive diabetics and hypertensive non-diabetics subjects studied, except for serum glucose that significantly higher (P<0.05) in hypertensive diabetics. It was observed that, mean concentrations of cholesterol, triglycerides (TG), LDC-cholesterol, as well as systolic blood pressure were significantly higher (P<0.05) in hypertensive diabetics compared with normal healthy individuals. The results also show that the mean HDL-cholesterol level was significantly lower (P>0.05) in hypertensive diabetics compared with normal healthy individuals. It was also illustrated that the concentrations of cholesterol, triglycerides, LDL-cholesterol systolic and diastolic blood pressure were significantly higher (P>0.05) in hypertensive non diabetics individuals compared with normal healthy individuals studied. However, the glucose and pulse rate mean levels showed no significant difference (P >0.05) between hypertensive non-diabetics and normal healthy individuals.
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