Doppler Echo-flowmetry of the Uterine District and Peeclampsia
Abstract
The Authors prospectively determined the uterine artery Doppler flow velocimetry between the 10th and 13th week of pregnancy in 32 women with history of HDP (Hypertensive Disorder of Pregnancy) in the attempt to identify those at higher risk to  develop preeclampsia during the ongoing pregnancy and the need for prophylactic  pharmacological treatment. Patients with abnormal flowmetric values (RI > 0.58)  were immediately started on aspirin 100 mg/daily followed at the 24th week by daily subcutaneous injection of low molecular weight heparin. The authors found that the average pregnancy course in terms of maternal morbidity (expressed by abnormal blood pressure and 24 hour proteinuria) in 20 prophylactic treated patients with abnormal 1st trimester uterine artery flowmetry was better than in their previous pregnancies, however in relation to the above parameters no significant difference was found between the patients treated and those (n =12) with normal I trimester uterine artery Doppler flowmetry who were also followed till delivery and 6 weeks post partum but not prophylactic treated. The study suggests that uterine artery flow velocimetry determination in the late first trimester of pregnancy is useful in reducing the risk of preeclampsia especially in patients with previous history of HDP allowing the prompt institution of prophylactic treatment in selected patients.
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