UV –Visible Spectroscopy Method Development and Its Validation for the Analysis of Marketed Hair Dyes for Amine Content
Keywords:Para Phenylenediamine , folins reagent Spectrophotometric method
To develop a simple rapid, accurate and spectrophotometric reproducible method were developed for estimation of PARA - PHENYLENE DIAMINE in different Marketed Hair dyes . The analysis of PPD was performed using NaOH solution as diluent and using folins reagent at 432nm respectively .The methods were linear in the concentration range from 0-50µg/ml. The methods were validated with respect to system suitability, linearity, precision, limit of detection, limit of quantification, accuracy, ruggedness and robustness . The developed method can be used for routine analysis of PARA PHENYLENE DIAMINE in marketed hair products. The methods were validated in accordance to the ICH guidelines.
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