Incidence and Antibiotic Resistance pattern of Bacteria associated with Wound infection in some Hospitals in Lagos, Nigeria.
Keywords:Wound infection, surgical wound, antibiotic susceptibility, Pseudomonas aeruginosa.
A total of 202 wound samples consisting of surgical, burn and accident/cut, collected randomly from patients in some hospitals in Lagos were examined using standard microbiological techniques. Wound infections were more prevalent in children and adolescent (0-20 years) with 96(48%) as against adults (21-40) with 64(32%) which declines from age 41-60 and above. A high incidence of bacterial isolates in wound was observed which were either pathogens or opportunistic pathogens. Pseudomonas aeruginosa, was the most frequently isolated bacterium with 128(40%), Enterobacter sp., 60(19%), Proteus mirabilis
56(18%), Escherichia coli, 20(6%) and Staphylococcus aureus, 16(5%). Accident/cut wounds constituted 52%, burn wounds, 32%, while surgical wounds accounted for only 16%. Antibiotic susceptibility studies with the disc diffusion technique on the bacterial isolates showed that most bacteria tested were resistant to amoxicillin, cotrimoxazole, nalidixic acid, augmentin, tetracycline and nitrofurantoin. However, in-vitro efficacy was shown by gentamicin and ofloxacin. Wounds independent of infection site led to
hospitalization for mostly 1-2 days (72%) while very few were hospitalized for over 5 days Â (10%).
Cleanliness and good personal hygiene should be taken seriously and enlightenment of the general public on the consequences of wound infection by our health care delivery system is strongly advocated.
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