Incidence and Antibiotic Resistance pattern of Bacteria associated with Wound infection in some Hospitals in Lagos, Nigeria.


  • D. D. Moro Department of Microbiology, Lagos StateUniversity,Ojo,P.M.B.1087,Apapa,Lagos,
  • H. O. Bello Department of Science Laboratory Technology, Gateway Polytechnic, Igbesa
  • S. O. Akano Department of Medical Microbiology, Olabisi Onabanjo University, Sagamu, Ogun



Wound infection, surgical wound, antibiotic susceptibility, Pseudomonas aeruginosa.


A total of 202 wound samples consisting of surgical, burn and accident/cut, collected randomly from patients in some hospitals in Lagos were examined using standard microbiological techniques. Wound infections were more prevalent in children and adolescent (0-20 years) with 96(48%) as against adults (21-40) with 64(32%) which declines from age 41-60 and above. A high incidence of bacterial isolates in wound was observed which were either pathogens or opportunistic pathogens. Pseudomonas aeruginosa, was the most frequently isolated bacterium with 128(40%), Enterobacter sp., 60(19%), Proteus mirabilis

56(18%), Escherichia coli, 20(6%) and Staphylococcus aureus, 16(5%). Accident/cut wounds constituted 52%, burn wounds, 32%, while surgical wounds accounted for only 16%. Antibiotic susceptibility studies with the disc diffusion technique on the bacterial isolates showed that most bacteria tested were resistant to amoxicillin, cotrimoxazole, nalidixic acid, augmentin, tetracycline and nitrofurantoin. However, in-vitro efficacy was shown by gentamicin and ofloxacin. Wounds independent of infection site led to

hospitalization for mostly 1-2 days (72%) while very few were hospitalized for over 5 days  (10%).

Cleanliness and good personal hygiene should be taken seriously and enlightenment of the general public on the consequences of wound infection by our health care delivery system is strongly advocated.


Thompson, JD. Counter attacking major infections. Health Care vol.8 no. 2 pp.1-4, 2004.

Jones, J. Examining the multifactorial nature of wound infection. Wound Essentials. Vol.2. pp. 90-9, 2012.

Bowler, PG, Duerden, BI and Armstrong DG. Wound microbiology and associated approaches to wound management. Clin. Microbiol. Rev. vol. 14. pp 244-269, 2001.

Collier, M. Understanding wound inflammation. Nursing Times, vol. 99, no.25. pp. 63-64, 2003.

Kingsley, A. A protective approach to wound infection. .Nurs. Scand. Vol. 15 no. 30, pp. 50-58, 2001.

Flaganam, M. Wound infection management A.C.E. series, Edinburgh , Churchill, Livingstone, 1997.

Nester, C., Evan, R., Pearsal, N., Deninese, G. ,Nester, M.J. A human perspective Microbiology, Ed. McGraw-Hill Publication, New York pp. 587-589, 1998.

Young T. Safe debridement in the community setting. Wound Essentials. Vol.2, pp. 82-89, 2012.

Cooper R. Understanding wound infection. In Cutting K, Gilchrist B, Gottrup F et al. Eds. Identifying criteria for wound infection. European Wound Management Association position document. MEP Ltd. London, 2005.

Donovan, S. Wound infection and wound swabbing. Prof. Nurs. Vol.12 no. 11, 1998.

Cheesbrough, M. Medical laboratory manual for tropical countries. Vol. II pp. 148-160, 2001.

Heinzamann, M., Scott M., Lam T. Factors predisposing to bacterial invasion and infection. Amer. J. Surg. Vol. 183 no.2, pp. 179-190, 2002.

Oni, A. A., Bakare, R.A., Okesola, A.O., Ounlowo, H.A. Pattern of bacterial pathogens in surgical wound infections. Afric. J. Med. & Med. Sci. vol. 26: pp.136-140, 1997.

Ogunsola F.T., Oduyebo O., Iregbu K.C., Coker A.O., Adetunji A.. A review of nosocomial infections at LUTH: Problems and strategies for improvement. Journal of Nigerian Infection Control Association, vol.1 pp.14-20, 1998.

Okesola, A.O., Oni, A.A., Bakare,R.A. Prevalence and antibiotic sensitivity pattern of methicillin-resistant Staphylococcus aureus in Ibadan, Nigeria. J. Hosp. Infect. Vol.41, pp.74-76, 1999.




How to Cite

Moro, D. D., Bello, H. O., & Akano, S. O. (2018). Incidence and Antibiotic Resistance pattern of Bacteria associated with Wound infection in some Hospitals in Lagos, Nigeria. Asian Journal of Applied Sciences, 6(4).