In Vitro Anti-melanogenesis and Collagen Biosynthesis Stimulating Activities of Star Grass (Hypoxis aurea Lour.) Extracts
Keywords:
Anti-melanogenesis, Collagen biosynthesis, Star Grass, Hypoxis aurea Lour.Abstract
Star Grass (SG) or Hypoxis aurea Lour. is the Thai traditional plant from genus Hypoxidaceae, which has been used to treat acnes, dark spots and blemish. However, there is no scientific report for bioactivity of SG especially the bioactivity claiming for cosmeceutical uses. This present study was investigated the anti-melanogenesis and collagen biosynthesis stimulating of the SG extracts, in order to evaluate the possible use as a whitening or anti-aging agent for cosmeceuticals. It was found that the phytochemicals detected in these extracts were glycosides (deoxysugars) and tannins. The leave extract from Star grass prepared by the maceration with 95%(v/v) ethanol at ambient temperature (SGLE) demonstrated the highest free radical scavenging activity by DPPH assay, tyrosinase inhibition activity by modified dopachrome method and anti-melanogenesis on B16F10 cells which was comparable to vitamin C (p< 0.05) ; and stimulation of collagen biosynthesis on human skin fibroblasts, which was superior than vitamin C (p< 0.05). This study has suggested that the leaves from Star grass extracted by 95%(v/v) ethanol (SGLE) can be applied as whitening and anti-aging agents for cosmeceuticals.
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