Effects of Extraction Solvents on Phytochemicals and Antibacterial Activities of <i>Garcinia mangostana</i> Pericarp
Keywords:Garcinia mangostana pericarp, Extraction solvents, Phytochemicals, Antibacterial activity
AbstractIn this paper, the effects of different solvents (hexane, ethyl acetate, acetone, ethanol, and methanol) on the content of phytochemicals including total polyphenols, flavonoids and anthocyanin, as well as antibacterial activities of extracts from Garcinia mangostana pericarp were investigated. The results showed that the contents of total polyphenols, flavonoids, and anthocyanin were significantly affected by extraction solvents, and resulting in variation of antibacterial activities of Garcinia mangostana pericarp. The methanol extract exhibited high antibacterial activities because it possessed the highest total polyphenols content. The acetone and ethanol extracts had the highest content of flavonoids and anthocyanin respectively and also exhibited higher antibacterial activities, while other extracts had both lower the content of active compounds and bioactivities. These results indicated that selective extraction from Garcinia mangostana pericarp, by an appropriate solvent, is important for obtaining fractions with high antibacterial activity, which will be useful for the developing and application of mangosteen pericarp as a new local source of bioactive compounds in foods and medicine industries.
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