Lung Cancer Risk Due to Radon in Different Brand Cigarette Tobacco in Iraqi Market

Abdalsattar Kareem Hashim, Fadhil Khaddam Fuliful

Abstract


Sealed can technique using CR-39 plastic track detector strippable has been used in order to measure radon concentrations to calculate the annual effective dose and lung cancer cases per year per million person for twenty different brand tobacco cigarette were collected from Iraqi market. Lung cancer is the leading cause of cancer-related deaths worldwide. Radon exposure is the second leading cause of lung cancer, following tobacco smoke. Radon is not only an independent risk factor; it also increases the risk of lung cancer in smokers.

It has been observed that tobacco smoking increases the risks of radon-induced lung cancer. Radon and cigarette smoking have synergistic, multiplicative effect on lung cancer rates. People who inhale tobacco smoke are exposed to higher concentrations of radioactivity. Ever since studies on the relation of smoking to cancer, particularly the lung cancer has been established, there had been a great interest in studies concerned with the monitoring of the alpha radioactivity in tobacco. The results showed that the 222Rn concentrations in cigarette tobacco samples ranged from (156.450  to 403.087)   Bq/m3 with an average 284.751  Bq/m3, while the radon induced lung cancer risks was found to vary from 71.047  to 183.049  with an av­erage value of 129.3107   per million person, and standard deviation 83.529 and 37.932, respectively. Excellent correlation has been observed between radon concentration and lung cancer cases per year per million person  for different brand tobacco cigarettes.

Keywords


Radon, tobacco, effective dose, lung cancer, CR-39, nuclear track detectors.

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References


World Health Organization. Global burden of disease. http://apps.who.int/ghodata/?vid=10012, 2008.

Hans Konrad Biesalski, Bas Bueno De Mesquita, Andrew Chesson, Frank Chytil, Robert Grimble, R. J. J. Hermus, Jochen Köhrle, Reuben Lotan, Karl Norpoth, Ugo Pastorino, and David Thurnham. European consensus statement on lung cancer: Risk factors and prevention, 1998.

International Agency for Research on Cancer. Monographs on the evaluation of carcinogenic risks to humans: Man-made mineral _bres and radon. http://monographs.iarc.fr/ENG/Monographs/vol43/volume43. pdf, 1988.

Swedish Radiation Safety Authority. Hur farligt är radon? Broschyr/2009/faktablad-hur-farligt-ar-radon.pdf, 2009.

CDC – Centers for Disease Control and prevention. Fact Sheet, # CDC 24/7 (www.cdc.gov/tobacco. Industry ), 2011.

Kuper H, Adami HO, Boffetta P. Tobacco use, cancer, causation and public health impact. J Inter Med 2002; 251:455-466.

Radon and Health, Canadian Nuclear Safety Commission (CNSC),Catalogue number: INFO-0813 ,2011

Mehra R, Singh S, Sigh K. A study of uranium, radium, radon exhalation rate and indoor radon in the environs of some areas of the Malwa region, Punjab. Indoor Built Environ 2006; 15:499-505.

Nain M, Chauhan RP, Chakarvarti SK. Alpha radioactivity in tobacco leaves: Effects of fertilizers. Radiat Meas 2008; 43:S515-S519.

Nain M, Gupta M, Chauhan RP, Kant K, Sonkawade RG, Chakarvarti SK. Estimation of radioactivity in tobacco. Ind J Pure Appl Phys 2010; 48:820-822.

UNSCEAR. Sources and effects of ionizing radiation. United Nations Publication E 94. 1X 1993; 2:33-89.

Alberigi S, Pecequilo RS, Lobo HAS, Campos MP. Assessment of effective doses from radon levels for tour guides at several galleries of Santana cave, Southern Brazil, with Cr-39 detectors: Preliminary results. Radiat Prot Dosim 2011; 54:1-4.

Ramola RC, Choubey VM. Measurement of radon exhalation rate from soil samples of Garhwal Himalaya, India. J Radioanal Nucl Chem 2003; 256:219-222.

Ramola RC, Negi MS, Choubey VM. Radon and thoron monitoring in the environment of Kumaun Himalayas: Survey and outcomes. J Environ Radioact 2005; 79:85-92.

Ramola RC, Prasad G, Prasad Y. Radon emanation from soil and groundwater and surface gamma dose rate in Budhakedar, Garhwal Himalayas, India. Indoor Built Environ 2007; 16:83-88.

Agency for Toxic Substances & Disease Registry. Toxicological pro_le for radon. http://www.atsdr.cdc.gov/ToxProfiles/tp.asp?id=407&tid= 71, 2008.

Alavanja MCR. Biological damage resulting from exposure to tobacco smoke and from radon: Implication for preventive interventions. Oncogene 2002; 21:7365-7375.

Sethi TK, El-Ghamry MN, Kloecker GH. Radon and lung cancer. Clin Adv in Hemat Oncol 2012; 10 :157- 64.

EPA -The U.S. Environmental Protection Agency. Action on radon cancer dangers, 2009.

International Agency for Research on Cancer. Monographs on the evaluation of carcinogenic risks to humans: Inorganic and organic lead compounds.http://monographs.iarc.fr/ENG/Monographs/vol87/ volume87.pdf, 2006.

Agency for Toxic Substances & Disease Registry. Toxicological pro_le for lead. http://www.atsdr.cdc.gov/ToxProfiles/tp.asp?id=96&tid=22, 2007.34 BIBLIOGRAPHY

R. L. Stedman. The chemical composition of tobacco and tobacco smoke. Chemical Review, 68(2):153_207, 1968.

R. Doll and A. B. Hill. Smoking and carcinoma of the lung. British Medical Journal, pages 740_748, 1950.

International Agency for Research on Cancer. Monographs on the evaluation of carcinogenic risks to humans: Tobacco smoking. http:// monographs.iarc.fr/ENG/Monographs/vol38/volume38.pdf, 1986.

Hans Konrad Biesalski, Bas Bueno De Mesquita, Andrew Chesson, Frank Chytil, Robert Grimble, R. J. J. Hermus, Jochen Köhrle, Reuben Lotan, Karl Norpoth, Ugo Pastorino, and David Thurnham. European consensus statement on lung cancer: Risk factors and prevention, 1998.

World Health Organization. Report on the global tobacco epidemic. http://www.who.int/tobacco/mpower/2009/gtcr_download/ en/index.html, 2009.

EPA. Assessment of risks from radon in homes. http://www.epa.gov/radiation/docs/assessment/402-r-03-003.pdf, 2003.

Swedish Radiation Safety Authority. Hur farligt är radon? http://www.stralsakerhetsmyndigheten.se/Global/Publikationer/Broschyr/2009/faktablad-hur-farligt-ar-radon.pdf, 2009.

P. Gehr and J. Heyder. Particle-lung interactions. Lung biology in health and disease. M. Dekker, 2000.

UNSCEAR. Sources and effects of ionizing radiation. United Nations Publication E 94. 1X 1993; 2:33-89.

Darby S. Radon in homes and risk of lung cancer: Collaborative analysis of individual data from 13 European case-control studies. BMJ 2005; 330:223-29.

Abu-Jarad F. Indoor cigarette smoking uranium contents and carrier of indoor radon products. Radiat Meas 1997; 28:579- 584.

Ghany HAA. The association between indoor radon and tobacco smoke. Indoor Built Environ 2006;15:289-293.

Misdaq MA, Flata K. Radon and daughters in cigarette smoke measured with SSNTD and corresponding committed equivalent dose to respiratory tract. Radiat Meas 2003; 37:31-38.

Ghany HAA. Enhancement of radon exposure in smoking area. Environ Geochem Health 2007; 29:249-255.

ACS – American Cancer Society. Smoking is the leading cause of lung cancer, 2004. (www.epa.gov/radon/healthrisks.html).

NRC – The National Research Council Report. Health effects of exposure to radon: BEIR VI , Committee on Health Risks of Exposure to Radon (BEIR VI), 1999. (www.epa.gov/radon/beirvi.html).

Lubin JH, Boice JD, Edling C. Lung cancer and radon – a joint analysis of 11 underground miners studies. National Cancer Institute: DHS Pub No (NIH)94- 3644, 1994.

EPA -The U.S. Environmental Protection Agency. Action on radon cancer dangers, 2009.

Saad AF, Abdalla YK, Hussein NA, Elyaseery IS. Radon exhalation rate from building materials used on the Garyounis University campus, Benghazi, Libya. Turkish J Eng Env Sci 2010;34:67-74.

Hamza, V. Z., Mohankumar, M. N., Cytogenetic damage in human blood lymphocytes exposed in vitro to radon, Mutation Research,661, (2009) pp.1-9

Abdalsattar Kareem Hashim and Elham Jasim Mohammed., Measurement of Radon Concentration and the Effective Dose Rate in the Soil of the City of Karbala, Iraq., J. Rad. Nucl. Appl. 1, No. 1, 17-23 (2016).

Somogi. G., Hafez. A., Hunyadi I. and Toth- Szilagyi M. Measurement of exhalation and diffusion parameters of radon in solids by plastic track detectors. Nucl. Track Radiat. Meas. 12,1-6,( 1986) 701-704.

Al-Bataina, B., Ismail, A., Kullab, M., Abumurad, K. and Mustafa, H., Radon measurements in different types of natural waters in Jordan. Radiation Measurement, 28(1) (1997) 591.

Ismail A.,H., Jaafar M.,S., " Indoor Radon concentration and its Health Risks in Selected Locations in Iraqi Kurdistan using CR-39 NTDs" Bioinformatics and Biomedical Engineering (iCBBE) , ldo 4th international Conference in Cheng du ,18-20 June, (2010).

Ismail A.,H.and Hussyin Z.,A.," Study of seasonal variations of radon levels and its risks inside different schools in Iraqi Kurdistan region for the first time" Proceeding of the 10th International Conference on Environmental Science and Technology" KOS island, Greece , 5- 7 September,B-305-B317, (2007).

Kansal S., Mehra R., Singh N.,P. " Life time fatality risk assessment due to variation of indoor radon concentration in dwellings in western Haryana, India" Applied Radiation and Isotopes, Vol.70, pp.1110-1112, (2012).

UNSCEAR. United Nations Scientific Committee on the Effects of Atomic Radiation: Sources and Effects of Ionizing Radiation, Vol.1.United Nations, New York, 2000.

ICRP (International Commission on Radiological Protection Publication), Protection against Radon-222 at home and at work.Annals of ICRP: Oxford: Pergamon press, pp.1-45, (1994).

Mowlavi A.,M., Fornasier M.R., Binesh A. and de Denaro M. " Indoor radon measurement and effective dose assessment of 150 apartments in Mashhad, Iran" Environ Monit Assess, Vol.184, pp.1085-1088, (2012) .

UNSCAER Appendix I: Epidemiological evaluation of radiation induced cancer; Appendix G: Biological effects of low radiation doses, (2000).

Abumurad, K. M., Al-Omari R. A., "Indoor radon levels in Irbid and health risks from internal doses. Radiation Measurements", Vol.43, pp.S389-S391, (2008).

Mansour H.H., "Measurement of indoor radon level in Arbil capital by using solid state nuclear track detectors " Radiation measurement Vol.40, pp: 544-547, (2005).

Abdullah,A.A., "Internal and external radiation exposure evaluation amongst selected workers and locations in Iraq" Ph.D. Thesis, University Sains Malaysia, Malaysia (2013).

ICRP, International Commission on Radiological Protection Statement on Radon. ICRP, Ref. 00/902/09, (2009).

UNSCEAR, "Genetic and somatic effects of ionizing radiation " ,United Nations, (1993).

ICRP, "Protection Against Rn-222 at Home and at Work" International Commission on Radiological Protection Publication 65. Ann. ICRP 23 (2). Pergamon Press; Oxford, (1993).

Abdalsattar Kareem Hashim, Laith Ahmed Najam, Lordford Tettey-Larbi., A Study of Radon Concentration in Different Brands Tobacco Cigarette in Iraqi Market, Influencing Factors and Lung Cancer Risk., International Journal of Science and Technology, Volume 5 No.10, October (2015).




DOI: https://doi.org/10.24203/ajas.v5i3.4768

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